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Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferation

Connexin 37 (Cx37) suppresses cell proliferation when expressed in rat insulinoma (Rin) cells, an effect also manifest in vivo during vascular development and in response to tissue injury. Mutant forms of Cx37 with nonfunctional channels but normally localized, wild-type carboxy termini are not grow...

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書誌詳細
主要な著者: Nelson, Tasha K., Sorgen, Paul L., Burt, Janis M.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882364/
https://ncbi.nlm.nih.gov/pubmed/24133065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00159.2013
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