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A functional channel is necessary for growth suppression by Cx37
Connexin 37 (Cx37) profoundly suppresses the proliferation of rat insulinoma (Rin) cells by unknown mechanisms. To determine whether a functional pore domain is necessary for Cx37-mediated growth suppression, we introduced a mutation that converted threonine 154 into alanine (T154A). Like other conn...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3124374/ https://ncbi.nlm.nih.gov/pubmed/21693589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.081695 |
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