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Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferation

Connexin 37 (Cx37) suppresses cell proliferation when expressed in rat insulinoma (Rin) cells, an effect also manifest in vivo during vascular development and in response to tissue injury. Mutant forms of Cx37 with nonfunctional channels but normally localized, wild-type carboxy termini are not grow...

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Detalhes bibliográficos
Main Authors: Nelson, Tasha K., Sorgen, Paul L., Burt, Janis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882364/
https://ncbi.nlm.nih.gov/pubmed/24133065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00159.2013
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