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Regulation of Cx37 channel and growth-suppressive properties by phosphorylation

Growth suppression mediated by connexin 37 (Cx37; also known as GJA4) requires interaction between its C-terminus and functional pore-forming domain. Using rat insulinoma cells, we show that Cx37 induces cell death and cell cycle arrest, and slowed cell cycling. Whether differential phosphorylation...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Cell Sci
Päätekijät: Jacobsen, Nicole L., Pontifex, Tasha K., Li, Hanjun, Solan, Joell L., Lampe, Paul D., Sorgen, Paul L., Burt, Janis M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Ltd 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665438/
https://ncbi.nlm.nih.gov/pubmed/28818996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.202572
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