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Challenges of creating effective CARs for cancer therapy

The immune system has the ability to recognize and attack tumor cells based on the expression or over-expression of specific antigens, but immune cells often express receptors that poorly recognize tumor antigens. However, recombinant DNA techniques combined with knowledge of immune signaling has pr...

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Detalhes bibliográficos
Autor principal: Sentman, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881530/
https://ncbi.nlm.nih.gov/pubmed/23902543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.13.71
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