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CAR Therapy for CLL: What are the Challenges?

Numerous targeted therapies are being developed for patients with CLL. CAR-modified T cells targeting CD19 expressed by normal and malignant B cells is a unique therapy and recent results from four different trials highlight the dramatic potential of this therapy for patients with relapsed CLL. Sinc...

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Detalhes bibliográficos
Main Authors: Davila, Marco L, Brentjens, Renier
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615434/
https://ncbi.nlm.nih.gov/pubmed/23561477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2012.12.004
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