A carregar...

A Preparation of (−)-Nutlin-3 Using Enantioselective Organocatalysis at Decagram Scale

[Image: see text] Chiral nonracemic cis-4,5-bis(aryl) imidazolines have emerged as a powerful platform for the development of cancer chemotherapeutics, stimulated by the Hoffmann-La Roche discovery that Nutlin-3 can restore apoptosis in cells with wild-type p53. The lack of efficient methods for the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Davis, Tyler A., Vilgelm, Anna E., Richmond, Ann, Johnston, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880828/
https://ncbi.nlm.nih.gov/pubmed/24127627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo401321a
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!