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HRES-1/Rab4 Promotes the Formation of LC3(+) Autophagosomes and the Accumulation of Mitochondria during Autophagy
HRES-1/Rab4 is a small GTPase that regulates endocytic recycling. It has been colocalized to mitochondria and the mechanistic target of rapamycin (mTOR), a suppressor of autophagy. Since the autophagosomal membrane component microtubule-associated protein light chain 3 (LC3) is derived from mitochon...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880286/ https://ncbi.nlm.nih.gov/pubmed/24404161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084392 |
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