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Nascent transcript sequencing visualizes transcription at nucleotide resolution

Recent studies of transcription have revealed a level of complexity not previously appreciated even a few years ago, both in the intricate use of post-initiation control and the mass production of rapidly degraded transcripts. Dissection of these pathways requires strategies for precisely following...

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Détails bibliographiques
Auteurs principaux: Churchman, L. Stirling, Weissman, Jonathan S.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880149/
https://ncbi.nlm.nih.gov/pubmed/21248844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09652
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