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Splicing kinetics and coordination revealed by direct nascent RNA sequencing through nanopores
Understanding how splicing events are coordinated across numerous introns in metazoan RNA transcripts requires quantitative analyses of transient RNA processing events in living cells. We developed nanopore analysis of CO-transcriptional Processing (nano-COP), in which nascent RNAs are directly sequ...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060811/ https://ncbi.nlm.nih.gov/pubmed/31839405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.11.017 |
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