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Biomedical Impact of Splicing Mutations Revealed through Exome Sequencing
Splicing is a cellular mechanism, which dictates eukaryotic gene expression by removing the noncoding introns and ligating the coding exons in the form of a messenger RNA molecule. Alternative splicing (AS) adds a major level of complexity to this mechanism and thus to the regulation of gene express...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
ScholarOne
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324954/ https://ncbi.nlm.nih.gov/pubmed/22160217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00126 |
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