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Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia.

To study the involvement of cyclin D1 in epithelial growth and differentiation and its putative role as an oncogene in skin, transgenic mice were developed carrying the human cyclin D1 gene driven by a bovine keratin 5 promoter. As expected, all squamous epithelia including skin, oral mucosa, trache...

詳細記述

保存先:
書誌詳細
主要な著者: Robles, A I, Larcher, F, Whalin, R B, Murillas, R, Richie, E, Gimenez-Conti, I B, Jorcano, J L, Conti, C J
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC38798/
https://ncbi.nlm.nih.gov/pubmed/8755527
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