Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia.

To study the involvement of cyclin D1 in epithelial growth and differentiation and its putative role as an oncogene in skin, transgenic mice were developed carrying the human cyclin D1 gene driven by a bovine keratin 5 promoter. As expected, all squamous epithelia including skin, oral mucosa, trache...

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Detaylı Bibliyografya
Asıl Yazarlar: Robles, A I, Larcher, F, Whalin, R B, Murillas, R, Richie, E, Gimenez-Conti, I B, Jorcano, J L, Conti, C J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC38798/
https://ncbi.nlm.nih.gov/pubmed/8755527
Etiketler: Etiketle
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