Učitavanje...

Inhibition of p38 Mitogen-activated Protein Kinase Impairs Influenza Virus-induced Primary and Secondary Host Gene Responses and Protects Mice from Lethal H5N1 Infection

Highly pathogenic avian influenza viruses (HPAIV) induce severe inflammation in poultry and men. One characteristic of HPAIV infections is the induction of a cytokine burst that strongly contributes to viral pathogenicity. This cell-intrinsic hypercytokinemia seems to involve hyperinduction of p38 m...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Börgeling, Yvonne, Schmolke, Mirco, Viemann, Dorothee, Nordhoff, Carolin, Roth, Johannes, Ludwig, Stephan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879537/
https://ncbi.nlm.nih.gov/pubmed/24189062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469239
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!