Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression

The type I interferon (IFN) system is a first line of defense against viral infections. Viruses have developed various mechanisms to counteract this response. So far, the interferon antagonistic activity of influenza A viruses was mainly observed on the level of IFNβ gene induction via action of the...

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Hauptverfasser: Pauli, Eva-K., Schmolke, Mirco, Wolff, Thorsten, Viemann, Dorothee, Roth, Johannes, Bode, Johannes G., Ludwig, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572141/
https://ncbi.nlm.nih.gov/pubmed/18989459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000196
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