WRB and CAML Are Necessary and Sufficient to Mediate Tail-Anchored Protein Targeting to the ER Membrane

Tail-Anchored (TA) proteins are inserted into the endoplasmic reticulum (ER) membrane of yeast cells via the posttranslational Guided Entry of Tail-Anchored protein (GET) pathway. The key component of this targeting machinery is the ATPase Get3 that docks to the ER membrane by interacting with a rec...

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Bibliographic Details
Main Authors: Vilardi, Fabio, Stephan, Milena, Clancy, Anne, Janshoff, Andreas, Schwappach, Blanche
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879356/
https://ncbi.nlm.nih.gov/pubmed/24392163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085033
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