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Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins

Tail-anchored (TA) proteins are characterized by a C-terminal transmembrane region that mediates posttranslational insertion into the membrane of the endoplasmic reticulum. We have investigated the requirements for membrane insertion of three TA proteins, RAMP4, Sec61β and cytochrome b5. We show her...

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Main Authors: Favaloro, Vincenzo, Spasic, Milan, Schwappach, Blanche, Dobberstein, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727622/
https://ncbi.nlm.nih.gov/pubmed/18477612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020321
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