OxLDL Induces PiT-1 Expression in Human Aortic Valve Interstitial Cells

BACKGROUND: The aortic valve interstitial cell (AVIC) has been implicated in the pathogenesis of calcific aortic stenosis. When appropriately stimulated, AVICs undergo a phenotypic change from that of a myofibroblast to that of a bone-forming-like cell. Elevated blood levels of LDL-cholesterol are a...

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Hlavní autoři: Nadlonek, Nicole A., Lee, Joon H., Weyant, Michael J., Meng, Xianzhong, Fullerton, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879113/
https://ncbi.nlm.nih.gov/pubmed/23849774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.05.001
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