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The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children

One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which...

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Bibliographic Details
Main Authors: Seven, Mehmet, Batar, Bahadir, Unal, Selin, Yesil, Gozde, Yuksel, Adnan, Guven, Mehmet
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877425/
https://ncbi.nlm.nih.gov/pubmed/24213830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-013-2866-y
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