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The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children

One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which...

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Hlavní autoři: Seven, Mehmet, Batar, Bahadir, Unal, Selin, Yesil, Gozde, Yuksel, Adnan, Guven, Mehmet
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877425/
https://ncbi.nlm.nih.gov/pubmed/24213830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-013-2866-y
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