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The drug-transporter gene MDR1 C3435T and G2677T/A polymorphisms and the risk of multidrug-resistant epilepsy in Turkish children

One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which...

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Autors principals: Seven, Mehmet, Batar, Bahadir, Unal, Selin, Yesil, Gozde, Yuksel, Adnan, Guven, Mehmet
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877425/
https://ncbi.nlm.nih.gov/pubmed/24213830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-013-2866-y
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