Detection of C1236T, G2677T/A, and C3435T polymorphism of MDR1 by amplification refractory mutation system PCR

C1236T, G2677T/A, and C3435T polymorphism of the multidrug resistance (MDR1) gene have substantial impact on expression or activity of P‐glycoprotein (P‐gp). We developed new methods based on amplification refractory mutation system (ARMS) to detect these polymorphisms. Tetra‐primers amplification i...

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Bibliographic Details
Published in:J Clin Lab Anal
Main Authors: Chen, Bing, Fang, Jie, Zhang, Weixia, Jin, Zhao, Yu, Zichen, Cai, Weimin
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648974/
https://ncbi.nlm.nih.gov/pubmed/19288456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.20299
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