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Detection of C1236T, G2677T/A, and C3435T polymorphism of MDR1 by amplification refractory mutation system PCR

C1236T, G2677T/A, and C3435T polymorphism of the multidrug resistance (MDR1) gene have substantial impact on expression or activity of P‐glycoprotein (P‐gp). We developed new methods based on amplification refractory mutation system (ARMS) to detect these polymorphisms. Tetra‐primers amplification i...

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發表在:J Clin Lab Anal
Main Authors: Chen, Bing, Fang, Jie, Zhang, Weixia, Jin, Zhao, Yu, Zichen, Cai, Weimin
格式: Artigo
語言:Inglês
出版: Wiley Subscription Services, Inc., A Wiley Company 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648974/
https://ncbi.nlm.nih.gov/pubmed/19288456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.20299
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