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GIT1 Activates p21-Activated Kinase through a Mechanism Independent of p21 Binding
p21-activated kinases (PAKs) associate with a guanine nucleotide exchange factor, Pak-interacting exchange factor (PIX), which in turn binds the paxillin-associated adaptor GIT1 that targets the complex to focal adhesions. Here, a detailed structure-function analysis of GIT1 reveals how this multido...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387736/ https://ncbi.nlm.nih.gov/pubmed/15082779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.9.3849-3859.2004 |
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