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CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer's Disease

BACKGROUND: CHRNA7 encodes the α7 nicotinic acetylcholine receptor subunit, which is important to Alzheimer's disease (AD) pathogenesis and cholinergic neurotransmission. Previously, CHRNA7 polymorphisms have not been related to cholinesterase inhibitors (ChEI) response. METHODS: Mild to modera...

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Détails bibliographiques
Auteurs principaux: Weng, Pei-Hsuan, Chen, Jen-Hau, Chen, Ta-Fu, Sun, Yu, Wen, Li-Li, Yip, Ping-Keung, Chu, Yi-Min, Chen, Yen-Ching
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877150/
https://ncbi.nlm.nih.gov/pubmed/24391883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084059
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