Sequence variants of interleukin 6 (IL-6) are significantly associated with a decreased risk of late-onset Alzheimer's disease

BACKGROUND: Interleukin 6 (IL-6) has been related to beta-amyloid aggregation and the appearance of hyperphosphorylated tau in Alzheimer's disease (AD) brain. However, previous studies relating IL-6 genetic polymorphisms to AD included few and unrepresentative single nucleotide polymorphisms (S...

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Detalhes bibliográficos
Main Authors: Chen, Shih-Yuan, Chen, Ta-Fu, Lai, Liang-Chuan, Chen, Jen-Hau, Sun, Yu, Wen, Li-Li, Yip, Ping-Keung, Chu, Yi-Min, Chen, Yen-Ching
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315433/
https://ncbi.nlm.nih.gov/pubmed/22272811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-21
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