Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer’s Disease

Previous genome-wide association studies using P-values to select single nucleotide polymorphisms (SNPs) have suffered from high false-positive and false-negative results. This case-control study recruited 713 late-onset Alzheimer’s disease (LOAD) cases and controls aged ≥65 from three teaching hosp...

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Vydáno v:Sci Rep
Hlavní autoři: Chen, Yen-Ching, Hsiao, Chi-Jung, Jung, Chien-Cheng, Hu, Hui-Han, Chen, Jen-Hau, Lee, Wen-Chung, Chiou, Jeng-Min, Chen, Ta-Fu, Sun, Yu, Wen, Li-Li, Yip, Ping-Keung, Chu, Yi-Min, Chen, Chien-Jen, Yang, Hwai-I
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090242/
https://ncbi.nlm.nih.gov/pubmed/27805002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36155
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