A Genetically Encoded Reporter for Real-Time Imaging of Cofilin-Actin Rods in Living Neurons

Filament bundles (rods) of cofilin and actin (1:1) form in neurites of stressed neurons where they inhibit synaptic function. Live-cell imaging of rod formation is hampered by the fact that overexpression of a chimera of wild type cofilin with a fluorescent protein causes formation of spontaneous an...

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Detalhes bibliográficos
Main Authors: Mi, Jianjie, Shaw, Alisa E., Pak, Chi W., Walsh, Keifer P., Minamide, Laurie S., Bernstein, Barbara W., Kuhn, Thomas B., Bamburg, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877059/
https://ncbi.nlm.nih.gov/pubmed/24391794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083609
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