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Incorporation of Cofilin into Rods Depends on Disulfide Intermolecular Bonds: Implications for Actin Regulation and Neurodegenerative Disease

Rod-shaped aggregates (“rods”), containing equimolar actin and the actin dynamizing protein cofilin, appear in neurons following a wide variety of potentially oxidative stress: simulated microischemia, cofilin overexpression, and exposure to peroxide, excess glutamate, or the dimer/trimer forms of a...

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Detalhes bibliográficos
Main Authors: Bernstein, Barbara W., Shaw, Alisa E., Minamide, Laurie S., Pak, Chi W., Bamburg, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745285/
https://ncbi.nlm.nih.gov/pubmed/22573689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6020-11.2012
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