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Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

BACKGROUND: High expression of CD161 on CD8+ T cells is associated with a population of cells thought to play a role in mucosal immunity. We wished to investigate this subset in an HIV and Mycobacterium tuberculosis (MTB) endemic African setting. METHODS: A flow cytometric approach was used to asses...

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Hlavní autoři: Wong, Emily B., Akilimali, Ngomu Akeem, Govender, Pamla, Sullivan, Zuri A., Cosgrove, Cormac, Pillay, Mona, Lewinsohn, David M., Bishai, William R., Walker, Bruce D., Ndung'u, Thumbi, Klenerman, Paul, Kasprowicz, Victoria O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877057/
https://ncbi.nlm.nih.gov/pubmed/24391773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083474
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