Early and nonreversible decrease of CD161(++)/MAIT cells in HIV infection

HIV infection is associated with immune dysfunction, perturbation of immune-cell subsets and opportunistic infections. CD161(++)CD8(+) T cells are a tissue-infiltrating population that produce IL17A, IL22, IFNγ, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the...

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Detalhes bibliográficos
Main Authors: Cosgrove, Cormac, Ussher, James E., Rauch, Andri, Gärtner, Kathleen, Kurioka, Ayako, Hühn, Michael H., Adelmann, Krista, Kang, Yu-Hoi, Fergusson, Joannah R., Simmonds, Peter, Goulder, Philip, Hansen, Ted H., Fox, Julie, Günthard, Huldrych F., Khanna, Nina, Powrie, Fiona, Steel, Alan, Gazzard, Brian, Phillips, Rodney E., Frater, John, Uhlig, Holm, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567342/
https://ncbi.nlm.nih.gov/pubmed/23255555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-436436
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