MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

Mucosal-associated invariant T (MAIT) cells are an innate-like T-cell population restricted by the non-polymorphic, major histocompatibility complex class I-related protein 1, MR1. MAIT cells are activated by a broad range of bacteria through detection of riboflavin metabolites bound by MR1, but the...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Kurioka, A, Ussher, J E, Cosgrove, C, Clough, C, Fergusson, J R, Smith, K, Kang, Y-H, Walker, L J, Hansen, T H, Willberg, C B, Klenerman, P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288950/
https://ncbi.nlm.nih.gov/pubmed/25269706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.81
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