Early and nonreversible decrease of CD161(++)/MAIT cells in HIV infection

HIV infection is associated with immune dysfunction, perturbation of immune-cell subsets and opportunistic infections. CD161(++)CD8(+) T cells are a tissue-infiltrating population that produce IL17A, IL22, IFNγ, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the...

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Hlavní autoři: Cosgrove, Cormac, Ussher, James E., Rauch, Andri, Gärtner, Kathleen, Kurioka, Ayako, Hühn, Michael H., Adelmann, Krista, Kang, Yu-Hoi, Fergusson, Joannah R., Simmonds, Peter, Goulder, Philip, Hansen, Ted H., Fox, Julie, Günthard, Huldrych F., Khanna, Nina, Powrie, Fiona, Steel, Alan, Gazzard, Brian, Phillips, Rodney E., Frater, John, Uhlig, Holm, Klenerman, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567342/
https://ncbi.nlm.nih.gov/pubmed/23255555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-436436
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