Early and nonreversible decrease of CD161(++)/MAIT cells in HIV infection

HIV infection is associated with immune dysfunction, perturbation of immune-cell subsets and opportunistic infections. CD161(++)CD8(+) T cells are a tissue-infiltrating population that produce IL17A, IL22, IFNγ, and TNFα, cytokines important in mucosal immunity. In adults they dominantly express the...

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Autors principals: Cosgrove, Cormac, Ussher, James E., Rauch, Andri, Gärtner, Kathleen, Kurioka, Ayako, Hühn, Michael H., Adelmann, Krista, Kang, Yu-Hoi, Fergusson, Joannah R., Simmonds, Peter, Goulder, Philip, Hansen, Ted H., Fox, Julie, Günthard, Huldrych F., Khanna, Nina, Powrie, Fiona, Steel, Alan, Gazzard, Brian, Phillips, Rodney E., Frater, John, Uhlig, Holm, Klenerman, Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2013
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567342/
https://ncbi.nlm.nih.gov/pubmed/23255555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-436436
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