Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality

The ability of antigen-specific T cells to simultaneously produce multiple cytokines is thought to correlate with the functional capacity and efficacy of T cells. These ‘polyfunctional’ T cells have been associated with control of HIV. We aimed to assess the impact of co-infection with Mycobacterium...

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Vydáno v:PLoS One
Hlavní autoři: Chetty, Shivan, Govender, Pamla, Zupkosky, Jennifer, Pillay, Mona, Ghebremichael, Musie, Moosa, Mahomed-Yunus S., Ndung’u, Thumbi, Porichis, Filippos, Kasprowicz, Victoria O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363785/
https://ncbi.nlm.nih.gov/pubmed/25781898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118654
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