Prospective Monitoring Reveals Dynamic Levels of T Cell Immunity to Mycobacterium Tuberculosis in HIV Infected Individuals

Monitoring of latent Mycobacterium tuberculosis infection may prevent disease. We tested an ESAT-6 and CFP-10-specific IFN-γ Elispot assay (RD1-Elispot) on 163 HIV-infected individuals living in a TB-endemic setting. An RD1-Elispot was performed every 3 months for a period of 3–21 months. 62% of RD1...

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Detalhes bibliográficos
Main Authors: Mitchell, Jessica E., Chetty, Shivan, Govender, Pamla, Pillay, Mona, Jaggernath, Manjeetha, Kasmar, Anne, Ndung’u, Thumbi, Klenerman, Paul, Walker, Bruce D., Kasprowicz, Victoria O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369919/
https://ncbi.nlm.nih.gov/pubmed/22685549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037920
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