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High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells

Mucosa-associated invariant T (MAIT) cells express the semi-invariant T-cell receptor TRAV1–2 and detect a range of bacteria and fungi through the MHC-like molecule MR1. However, knowledge of the function and phenotype of bacteria-reactive MR1-restricted TRAV1–2(+) MAIT cells from human blood is lim...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Sharma, Prabhat K, Wong, Emily B, Napier, Ruth J, Bishai, William R, Ndung'u, Thumbi, Kasprowicz, Victoria O, Lewinsohn, Deborah A, Lewinsohn, David M, Gold, Marielle C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479542/
https://ncbi.nlm.nih.gov/pubmed/25752900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12461
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