Association between a Genetic Variant of Type-1 Cannabinoid Receptor and Inflammatory Neurodegeneration in Multiple Sclerosis

Genetic ablation of type-1 cannabinoid receptors (CB(1)Rs) exacerbates the neurodegenerative damage of experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS). To address the role on CB(1)Rs in the pathophysiology of human MS, we first investigated the impact of AAT tr...

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Main Authors: Rossi, Silvia, Bozzali, Marco, Bari, Monica, Mori, Francesco, Studer, Valeria, Motta, Caterina, Buttari, Fabio, Cercignani, Mara, Gravina, Paolo, Mastrangelo, Nicolina, Castelli, Maura, Mancino, Raffaele, Nucci, Carlo, Sottile, Fabrizio, Bernardini, Sergio, Maccarrone, Mauro, Centonze, Diego
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877004/
https://ncbi.nlm.nih.gov/pubmed/24391723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082848
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