Association between a Genetic Variant of Type-1 Cannabinoid Receptor and Inflammatory Neurodegeneration in Multiple Sclerosis

Genetic ablation of type-1 cannabinoid receptors (CB(1)Rs) exacerbates the neurodegenerative damage of experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS). To address the role on CB(1)Rs in the pathophysiology of human MS, we first investigated the impact of AAT tr...

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Hlavní autoři: Rossi, Silvia, Bozzali, Marco, Bari, Monica, Mori, Francesco, Studer, Valeria, Motta, Caterina, Buttari, Fabio, Cercignani, Mara, Gravina, Paolo, Mastrangelo, Nicolina, Castelli, Maura, Mancino, Raffaele, Nucci, Carlo, Sottile, Fabrizio, Bernardini, Sergio, Maccarrone, Mauro, Centonze, Diego
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877004/
https://ncbi.nlm.nih.gov/pubmed/24391723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082848
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