Association between a Genetic Variant of Type-1 Cannabinoid Receptor and Inflammatory Neurodegeneration in Multiple Sclerosis

Genetic ablation of type-1 cannabinoid receptors (CB(1)Rs) exacerbates the neurodegenerative damage of experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS). To address the role on CB(1)Rs in the pathophysiology of human MS, we first investigated the impact of AAT tr...

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Bibliografiska uppgifter
Huvudupphovsmän: Rossi, Silvia, Bozzali, Marco, Bari, Monica, Mori, Francesco, Studer, Valeria, Motta, Caterina, Buttari, Fabio, Cercignani, Mara, Gravina, Paolo, Mastrangelo, Nicolina, Castelli, Maura, Mancino, Raffaele, Nucci, Carlo, Sottile, Fabrizio, Bernardini, Sergio, Maccarrone, Mauro, Centonze, Diego
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877004/
https://ncbi.nlm.nih.gov/pubmed/24391723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082848
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