Association between a Genetic Variant of Type-1 Cannabinoid Receptor and Inflammatory Neurodegeneration in Multiple Sclerosis

Genetic ablation of type-1 cannabinoid receptors (CB(1)Rs) exacerbates the neurodegenerative damage of experimental autoimmune encephalomyelitis, the rodent model of multiple sclerosis (MS). To address the role on CB(1)Rs in the pathophysiology of human MS, we first investigated the impact of AAT tr...

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Autors principals: Rossi, Silvia, Bozzali, Marco, Bari, Monica, Mori, Francesco, Studer, Valeria, Motta, Caterina, Buttari, Fabio, Cercignani, Mara, Gravina, Paolo, Mastrangelo, Nicolina, Castelli, Maura, Mancino, Raffaele, Nucci, Carlo, Sottile, Fabrizio, Bernardini, Sergio, Maccarrone, Mauro, Centonze, Diego
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877004/
https://ncbi.nlm.nih.gov/pubmed/24391723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082848
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