Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies

BACKGROUND: Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits. METHODS: We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI algorithm. Heritability and...

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Autores principales: Pasha, Dalal N., Davis, Jason T., Rao, Fangwen, Chen, Yuqing, Wen, Gen, Fung, Maple M., Mahata, Manjula, Zhang, Kuixing, Trzebinska, Danuta, Mustapic, Maja, Hightower, C. Makena, Lipkowitz, Michael S., Ji, Ming, Ziegler, Michael G., Nievergelt, Caroline M., O'Connor, Daniel T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876991/
https://ncbi.nlm.nih.gov/pubmed/24391727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082956
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