Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies

BACKGROUND: Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits. METHODS: We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI algorithm. Heritability and...

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Detalhes bibliográficos
Main Authors: Pasha, Dalal N., Davis, Jason T., Rao, Fangwen, Chen, Yuqing, Wen, Gen, Fung, Maple M., Mahata, Manjula, Zhang, Kuixing, Trzebinska, Danuta, Mustapic, Maja, Hightower, C. Makena, Lipkowitz, Michael S., Ji, Ming, Ziegler, Michael G., Nievergelt, Caroline M., O'Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876991/
https://ncbi.nlm.nih.gov/pubmed/24391727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082956
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