Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies

BACKGROUND: Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits. METHODS: We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI algorithm. Heritability and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pasha, Dalal N., Davis, Jason T., Rao, Fangwen, Chen, Yuqing, Wen, Gen, Fung, Maple M., Mahata, Manjula, Zhang, Kuixing, Trzebinska, Danuta, Mustapic, Maja, Hightower, C. Makena, Lipkowitz, Michael S., Ji, Ming, Ziegler, Michael G., Nievergelt, Caroline M., O'Connor, Daniel T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876991/
https://ncbi.nlm.nih.gov/pubmed/24391727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082956
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