Heritable Influence of DBH on Adrenergic and Renal Function: Twin and Disease Studies

BACKGROUND: Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits. METHODS: We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI algorithm. Heritability and...

Full description

Saved in:
Bibliographic Details
Main Authors: Pasha, Dalal N., Davis, Jason T., Rao, Fangwen, Chen, Yuqing, Wen, Gen, Fung, Maple M., Mahata, Manjula, Zhang, Kuixing, Trzebinska, Danuta, Mustapic, Maja, Hightower, C. Makena, Lipkowitz, Michael S., Ji, Ming, Ziegler, Michael G., Nievergelt, Caroline M., O'Connor, Daniel T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876991/
https://ncbi.nlm.nih.gov/pubmed/24391727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082956
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items