Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis

Background. End-stage renal disease (ESRD) due to hypertension is common and displays familial aggregation in African Americans, suggesting genetic risk factors, including adrenergic activity alterations which are noted in both hypertension and ESRD. Methods. We analysed 554 hypertensive nephroscler...

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Autors principals: Fung, Maple M., Chen, Yuqing, Lipkowitz, Michael S., Salem, Rany M., Bhatnagar, Vibha, Mahata, Manjula, Nievergelt, Caroline M., Rao, Fangwen, Mahata, Sushil K., Schork, Nicholas J., Brophy, Victoria H., O’Connor, Daniel T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Clinical Nephrology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790952/
https://ncbi.nlm.nih.gov/pubmed/19745105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp471
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