Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC)

BACKGROUND. Hyperhomocysteinemia is associated with increased venous thrombosis and cardiovascular disease (CVD). Mutations in the human methylenetetrahydrofolate reductase (MTHFR) gene have been associated with increased homocysteine levels and risks of CVD in various populations including those wi...

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Detalhes bibliográficos
Main Authors: Fung, Maple M., Salem, Rany M., Lipkowitz, Michael S., Bhatnagar, Vibha, Pandey, Braj, Schork, Nicholas J., O’Connor, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350339/
https://ncbi.nlm.nih.gov/pubmed/21613384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfr257
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