Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC)

BACKGROUND. Hyperhomocysteinemia is associated with increased venous thrombosis and cardiovascular disease (CVD). Mutations in the human methylenetetrahydrofolate reductase (MTHFR) gene have been associated with increased homocysteine levels and risks of CVD in various populations including those wi...

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Détails bibliographiques
Auteurs principaux: Fung, Maple M., Salem, Rany M., Lipkowitz, Michael S., Bhatnagar, Vibha, Pandey, Braj, Schork, Nicholas J., O’Connor, Daniel T.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350339/
https://ncbi.nlm.nih.gov/pubmed/21613384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfr257
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