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A Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A Inhibitors

Despite increasing recognition of potential untoward interactions between herbal products and conventional medications, a standard system for prospective assessment of these interactions remains elusive. This information gap was addressed by evaluating the drug interaction liability of the model her...

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Bibliografiske detaljer
Main Authors: Brantley, Scott J., Graf, Tyler N., Oberlies, Nicholas H., Paine, Mary F.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876807/
https://ncbi.nlm.nih.gov/pubmed/23801821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.052563
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