Two Flavonolignans from Milk Thistle (Silybum marianum) Inhibit CYP2C9-Mediated Warfarin Metabolism at Clinically Achievable Concentrations

Milk thistle (Silybum marianum) is a popular herbal product used for hepatoprotection and chemoprevention. Two commercially available formulations are the crude extract, silymarin, and the semipurified product, silibinin. Silymarin consists of at least seven flavonolignans, of which the most prevale...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brantley, Scott J., Oberlies, Nicholas H., Kroll, David J., Paine, Mary F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2010
Gaiak:
Metabolism, Transport, and Pharmacogenomics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835426/
https://ncbi.nlm.nih.gov/pubmed/19934397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.161927
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