NLRP3 Inflammasome Knockout Mice Are Protected against Ischemic but Not Cisplatin-Induced Acute Kidney Injury

We have demonstrated that caspase-1 is a mediator of both cisplatin-induced acute kidney injury (AKI) and ischemic AKI. As caspase-1 is activated in the inflammasome, we investigated the inflammasome in cisplatin-induced and ischemic AKI. Mice were injected with cisplatin or subjected to bilateral r...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Kim, Hyun-Jung, Lee, Dong Won, Ravichandran, Kameswaran, O. Keys, Daniel, Akcay, Ali, Nguyen, Quocan, He, Zhibin, Jani, Alkesh, Ljubanovic, Danica, Edelstein, Charles L.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2013
נושאים:
Gastrointestinal, Hepatic, Pulmonary, and Renal
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876780/
https://ncbi.nlm.nih.gov/pubmed/23833276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.205732
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים