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SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines

SOCS3 is an inducible negative feedback inhibitor of cytokine signaling. Conditional deletion of SOCS3 in mice using the Cre-lox system has now been applied to a range of cell types in the steady-state and under inflammatory, pathogenic, or tumorigenic stress, with the resulting phenotypes demonstra...

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Autori principali: White, Christine A, Nicola, Nicos A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876435/
https://ncbi.nlm.nih.gov/pubmed/24416642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.25045
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