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The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment

Improper kinetochore attachments activate the spindle assembly checkpoint (SAC) to prevent anaphase onset, but it is poorly understood how this checkpoint is silenced to allow anaphase onset. Chromosome bipolar attachment applies tension on sister kinetochores, and the lack of tension delays anaphas...

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Main Authors: Jin, Fengzhi, Wang, Yanchang
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876237/
https://ncbi.nlm.nih.gov/pubmed/24324173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307595111
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