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The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment

Improper kinetochore attachments activate the spindle assembly checkpoint (SAC) to prevent anaphase onset, but it is poorly understood how this checkpoint is silenced to allow anaphase onset. Chromosome bipolar attachment applies tension on sister kinetochores, and the lack of tension delays anaphas...

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Detalhes bibliográficos
Main Authors: Jin, Fengzhi, Wang, Yanchang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876237/
https://ncbi.nlm.nih.gov/pubmed/24324173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307595111
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